Police are investigating the robbery of a liquor store in Brisbane City this afternoon.

Around 1.25pm two men entered the Roma Street store and engaged the male attendant in conversation before attempting to steal bottles of liquor.

The attendant confronted the men and a physical altercation ensued.

The men physically assaulted the attendant before he was struck over the head with a bottle.

The men fled on foot in possession of two bottles of liquor.

The attendant was transported to St Andrews Hospital suffering a laceration to his head and a contusion to his jaw.

Both men are described as Aboriginal in appearance, black hair, solid build, 185cms tall and aged in their mid twenties.

The first man was wearing black shorts with white stripes, a red jacket and white thongs.

The second man was wearing a grey polo shirt with white and black stripes, black shorts and black joggers.

Investigations are continuing.