Two men have been arrested following an alleged attempted theft from a Melbourne chemist this evening (26 November).

Police were called to the Bourke Street store about 8.50pm after reports two men had allegedly tried to steal some items.

It is alleged one of the men produced a knife and assaulted a security guard after being confronted.

The security guard sustained minor injuries.

The pair then fled the store empty-handed.

A 24-year-old Ferntree Gully man and 22-year-old Burwood man were arrested by police shortly after on Elizabeth Street.

They are currently in custody assisting police with their enquiries.

The investigation is ongoing.